I used to hear Don and Mike use the name to refer to any podunk town or out-of-the-way place, but now, through the wonder of the USGS Geographic Names Information System, I can definitively say that "Yes, Virginia, there is a Hooterville".

I am a little disappointed, though not terribly surprised, to report that there appear to be no place names beginning with "Fuck" or "Cunt", but that "Shit", or more specifically "Shite" is well-represented.